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HIV Prevention Knowledge Base

A Collection of Research and Tools to Help You Find What Works in Prevention

Biomedical Interventions: Diagnosis and Treatment of Sexually Transmitted Infections

Link to important additional materials and websites

Periodic Presumptive Treatment for Sexually Transmitted Infections: Experience from the Field and Recommendations for Research

World Health Organization. (2008).

This report describes experiences from the field in periodic and one-time presumptive treatment for sexually transmitted infections (STIs) among sex workers and their clients. The report followed on from a technical consultation on global experiences of presumptive STI treatment programs among high-risk populations. The consultation identified the conditions needed for effective STI control using presumptive treatment and produced recommendations for research. Both topics are covered in this report, as is the effect of presumptive treatment on specific STIs. The report presents case studies and offers brief guidance on operating such programs.

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The Global Strategy for the Prevention and Control of Sexually Transmitted Infections 2006–2015: Breaking the Chain of Transmission

World Health Organization. (2007).

This document makes the case for a global strategy to tackle sexually transmitted infections (STIs), describing the public health burden and the opportunities for an accelerated response such as the emergence of new and cost-effective technologies. The strategy aims to provide a framework for this response and is targeted at managers of national HIV prevention and STI control programs as well as other health sector stakeholders including health care providers, health ministers, and donors. It details both the technical strategy for STI prevention and control and an advocacy strategy for mobilizing resources and political and social leadership.

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Guidelines for the Management of Sexually Transmitted Infections

World Health Organization. (2003).

These guidelines lay out the standardized treatment recommendations for syndromes associated with sexually transmitted infections (STIs) using at-a-glance flowcharts and tables. There are also treatment recommendations for each specific STI. The guidelines detail the main considerations in choosing a treatment, such as cost, efficacy, treatment compliance, and availability. There is a chapter covering practical considerations in case management of STIs and another on treatment of STIs in children and adolescents.

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