Infant Feeding for Mothers Living with HIV

Introduction
Summary: 

HIV can be transmitted from a mother to her child during pregnancy or delivery. When a mother is HIV infected, her baby can also be infected through breastfeeding.

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Updated: August 2010

I. Definition of the Prevention Area

HIV can be transmitted from a mother to her child during pregnancy or delivery. When a mother is HIV infected, her baby can also be infected through breastfeeding. Several interventions reduce the risk of transmission in the first two phases. Until recently, there was uncertainty regarding appropriate and healthy options for feeding infants of mothers living with HIV.

The 2010 World Health Organization (WHO) Guidelines on HIV and infant feeding have changed this landscape dramatically. The benefits of breastfeeding can now be achieved by mothers living with HIV, with a very low risk of transmitting HIV to the infant when breastfeeding is combined with maternal or infant antiretroviral (ARV) interventions. This avoids the risks associated with formula feeding and attains the ultimate goal of "HIV-free survival" for more infants.

II. Epidemiological Justification for the Prevention Area

Without interventions to prevent mother-to-child transmission, an estimated one-third of infants born to mothers living with HIV will become infected. Breastfeeding is responsible for 30 to 60 percent of the infections among children with HIV.

Mothers with high viral loads or low CD4 cell counts are most likely to transmit the virus during breastfeeding. Antiretroviral treatment before pregnancy or during early pregnancy and continuing postnatally can cut the risk of mother-to-child transmission by at least 75 percent. Other risk factors include mixed feeding (giving formula or other substances in addition to breast milk) in the first 6 months, various breast pathologies (such as mastitis, abscesses, or nipple lesions), and poor maternal nutrition.

III. Core Programmatic Components

The major programmatic options include promoting breastfeeding or formula feeding. Unfortunately, in regions with poor sanitation, unclean water used to mix formula has caused serious illness and deaths among formula-fed infants, who are more likely than breastfed infants to die from diarrhea, malnutrition, and serious infections. Alternatives such as heat treating expressed breast milk or providing breast milk from HIV-uninfected wet nurses are not practical in most resource-limited settings.

The 2010 WHO Guidelines advise national authorities to advocate a single infant feeding practice based on local conditions (socioeconomic and cultural contexts; availability and quality of health services; local epidemiology including HIV; the primary causes of infant and child mortality; and maternal and child undernutrition). Breastfeeding with antiretroviral (ARV) treatment/prophylaxis or avoidance of all breastfeeding are optimal choices. Most governments are expected to opt for breastfeeding with ARV treatment/prophylaxis. In resource-limited countries that have opted for breastfeeding as the primary option, exclusive breastfeeding for the first 6 months should be promoted even if ARV treatment or prophylaxis are not yet accessible; breastfeeding is not conditional on ARV treatment or prophylaxis.

Major messages in the 2010 WHO Guidelines for countries that opt for breastfeeding are:

WHO also promotes counseling and support for infant feeding and informed choice on the part of the mother. Support should not be contingent on whether a mother's choice aligns with national recommendations.

The absence of comprehensive and widely accessible postnatal care (including infant feeding) has been a major gap in PMTCT programs overall. These new WHO recommendations urgently need to be implemented in order to achieve the ultimate goal of "HIV-free survival" of infants.

IV. Current Status of Implementation Experience

Cultural barriers, financial and manpower constraints, and other obstacles made it difficult to implement maternal, newborn, and child health and PMTCT programs recommended by WHO in 2006. In many cases, counseling and support for women were inadequate. The stigma associated with HIV compromised the ability of women to breastfeed, and the cost and complexity of using formula created further barriers to implementation.

Successful implementation of the 2010 WHO Guidelines will require several steps: national guidelines and policies related to HIV and infant feeding will need to be changed; training curricula altered; new training provided for health workers; and efforts to secure community support reinforced.

Finally, efforts to widely promote breastfeeding for all mothers--which have been compromised in recent years due to fears about HIV transmission--will need to be reinvigorated.

 

Additional Resources: 

Rapid Advice: Use of Antiretroviral Drugs for Treating Pregnant Women and Preventing HIV Infection in Infants.

WHO. (2009).

These recently-updated, evidence-based recommendations on PMTCT serve as a reference for countries to adopt and adapt according to conditions found at the national level (resource availability and limitations, etc.). They are intended as an aid to simplify and standardize previous recommendations by making guidelines for initiating antiretroviral treatment (ART) for pregnant women the same as for non-pregnant women and by taking into account programmatic considerations that affect implementation. They provide guidance for policy makers and program managers responsible for PMTCT programs and are a resource for health workers involved in prevention, care, and treatment of pregnant women and their infants. These recommendations focus on two key areas: a) when to start ART and which regimen to use for pregnant women who are treatment-eligible (and their infants); and b) when to start and which antiretroviral prophylaxis regimen to give non treatment-eligible women (and their infants). Recommendations are given for breastfeeding and non-breastfeeding infants. These recommendations form part of a larger guideline which is expected to be published and disseminated in March-April 2010.

View Report (PDF, 428 KB)

View Report Summary (PDF, 128 KB)


State of the World's Children

UNICEF. (2009).

The tables found in the State of the World's Children report contain data for all countries as well as regional summaries on breastfeeding patterns.

View Report (PDF, 420 KB)

 

 

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Learn more

Rapid Advice: Use of Antiretroviral Drugs for Treating Pregnant Women and Preventing HIV Infection in Infants.

WHO. (2009).

These recently-updated, evidence-based recommendations on PMTCT serve as a reference for countries to adopt and adapt according to conditions found at the national level (resource availability and limitations, etc.). They are intended as an aid to simplify and standardize previous recommendations by making guidelines for initiating antiretroviral treatment (ART) for pregnant women the same as for non-pregnant women and by taking into account programmatic considerations that affect implementation. They provide guidance for policy makers and program managers responsible for PMTCT programs and are a resource for health workers involved in prevention, care, and treatment of pregnant women and their infants. These recommendations focus on two key areas: a) when to start ART and which regimen to use for pregnant women who are treatment-eligible (and their infants); and b) when to start and which antiretroviral prophylaxis regimen to give non treatment-eligible women (and their infants). Recommendations are given for breastfeeding and non-breastfeeding infants. These recommendations form part of a larger guideline which is expected to be published and disseminated in March-April 2010.

View Report (PDF, 428 KB)

View Report Summary (PDF, 128 KB)


State of the World's Children

UNICEF. (2009).

The tables found in the State of the World's Children report contain data for all countries as well as regional summaries on breastfeeding patterns.

View Report (PDF, 420 KB)